Phosphodiesterase Inhibitors/Nutrient Depletion:
- MelatoninMelatonin: Based on human and animal evidence, phosphodiesterase inhibitors like theophylline that reduce levels of vitamin B6 in the body may also deplete melatonin levels (11349394, 1806289).
- PotassiumPotassium: Based on human evidence, theophylline derivatives may lower serum potassium levels (7646822).
- Vitamin B6/pyridoxineVitamin B6/pyridoxine: Based on human evidence, theophylline may interfere with vitamin B6/pyridoxine metabolism (2535870).
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.