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Diuretics



Depletions

Tricyclic Antidepressants/Nutrient Depletion:
  • Coenzyme Q10Coenzyme Q10: According to secondary sources, antidepressants may reduce the natural production of CoQ10. Use of both agents, therefore, may result in diminished effects of CoQ10. Specific medications noted in anecdotal reports include amitripyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, and perphenazine.
  • RiboflavinRiboflavin: Based on animal studies, tricyclic antidepressants, such as imipramine, desimpramine, amitriptyline, and nortriptyline, may reduce levels of riboflavin in the body, possibly meriting supplementation (6262379).

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