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Marshmallow (Althaea officinalis)



Interactions

Marshmallow/Drug Interactions:
  • ACE inhibitorsACE inhibitors: In human research, marshmallow resulted in a reduction in angiotensin-converting enzyme (ACE) inhibitor-induced cough (13).
  • AntibioticsAntibiotics: In animal research, marshmallow exhibited antimicrobial activity against P. aeruginosa, P. vulgaris, and S. aureus (14; 15). According to secondary sources, marshmallow may interact with antibiotics.
  • Antidiabetic agentsAntidiabetic agents: In animal research, marshmallow had hypoglycemic effects (12).
  • Anti-inflammatory agentsAnti-inflammatory agents: In animal research, marshmallow had anti-inflammatory properties (16).
  • AntimicrobialsAntimicrobials: In animal research, marshmallow exhibited antimicrobial activity against P. aeruginosa, P. vulgaris, and S. aureus (14; 15).
  • AntiprotozoalsAntiprotozoals: In human research, a topical combination product containing marshmallow showed a curing effect for Old World cutaneous leishmaniasis (17).
  • AntitussivesAntitussives: In animal and laboratory research, marshmallow root extract and marshmallow polysaccharides had antitussive effects (18; 14; 19; 20). In human research, marshmallow resulted in a reduction in ACE inhibitor-induced cough (13).
  • GastrointestinalagentsGastrointestinalagents: According to secondary sources, marshmallow has been used for gastroenteritis, peptic and duodenal ulcers, and ulcerative colitis and theoretically may interact with gastrointestinal agents.
  • ImmunostimulantsImmunostimulants: According to secondary sources, marshmallow has been used as an immunostimulant and theoretically may interact with immunostimulant agents.
  • Oral drugsOral drugs: According to secondary sources, the fiber in marshmallow may impair absorption of oral drugs.
  • Topical steroidsTopical steroids: In human research, marshmallow increased the topical anti-inflammatory effects of steroids (1).

Marshmallow/Herb/Supplement Interactions:
  • AntibacterialsAntibacterials: In animal research, marshmallow exhibited antimicrobial activity against P. aeruginosa, P. vulgaris, and S. aureus (14; 15). According to secondary sources, marshmallow may interact with herbs and supplements with antibacterial properties.
  • Anti-inflammatory herbs and supplementsAnti-inflammatory herbs and supplements: In animal research, marshmallow had anti-inflammatory properties (16).
  • AntimicrobialsAntimicrobials: In animal research, marshmallow exhibited antimicrobial activity against P. aeruginosa, P. vulgaris, and S. aureus (14; 15).
  • AntiprotozoalsAntiprotozoals: In human research, a topical combination product containing marshmallow showed a curing effect for Old World cutaneous leishmaniasis (17).
  • Antitussive herbs and supplementsAntitussive herbs and supplements: In human research, marshmallow resulted in a reduction in ACE inhibitor-induced cough (13). In animal and laboratory research, marshmallow root extract and marshmallow polysaccharides had antitussive effects (18; 14; 19; 20).
  • HypoglycemicsHypoglycemics: In animal research, marshmallow had hypoglycemic effects (12).
  • Oral agentsOral agents: According to secondary sources, the fiber in marshmallow may impair absorption of oral drugs.

Marshmallow/Food Interactions:
  • Insufficient available evidence.

Marshmallow/Lab Interactions:
  • Serum glucoseSerum glucose: In animal research, marshmallow had a hypoglycemic effect (12).

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.