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Apple cider vinegar



Interactions

Apple cider vinegar/Drug Interactions:
  • Cardiac glycosidesCardiac glycosides: Based on potential pH altering effects of apple cider vinegar, long-term oral use of apple cider vinegar can decrease potassium levels, increasing the risk of toxicity of cardiac glycosides such as digoxin (Lanoxin®) (2).
  • Insulin preparationsInsulin preparations: Based on potential pH altering effects of apple cider vinegar, long-term oral use of apple cider vinegar can decrease potassium levels, and may add to the potassium-lowering effects of insulin (2).
  • LaxativesLaxatives: Based on potential pH altering effects of apple cider vinegar, long-term oral use of apple cider vinegar can decrease potassium levels, and may add to the potassium-lowering effects of laxatives (2).
  • Potassium-depleting diureticsPotassium-depleting diuretics: Based on potential pH altering effects of apple cider vinegar, long-term oral use of apple cider vinegar can decrease potassium levels, and may add to the potassium-lowering effects of diuretics such as furosemide (Lasix®) (2).
  • Potassium depleting drugsPotassium depleting drugs: Based on potential pH altering effects of apple cider vinegar, long-term oral use or high consumption of apple cider vinegar can decrease potassium levels, and may have additive effects with other agents that deplete potassium (2).

Apple cider vinegar/Herb/Supplement Interactions:
  • Cardiac glycoside herbsCardiac glycoside herbs: Based on potential pH altering effects of apple cider vinegar, long-term oral use of apple cider vinegar can decrease potassium levels, increasing the risk of toxicity of cardiac glycoside herbs (2).
  • DiureticsDiuretics: Based on potential pH altering effects of apple cider vinegar, long-term oral use of apple cider vinegar can decrease potassium levels, and may add to the potassium-lowering effects of diuretics (2).
  • LaxativesLaxatives: Based on potential pH altering effects of apple cider vinegar, long-term overuse of apple cider vinegar can decrease potassium levels, and may add to the potassium-lowering effects of laxative herbs (2).
  • Potassium depleting herbsPotassium depleting herbs: Based on potential pH altering effects of apple cider vinegar, long-term oral use of apple cider vinegar can decrease potassium levels, and may add to the potassium-lowering effects of certain herbs like horsetail (2).

Apple cider vinegar/Food Interactions:
  • Insufficient available evidence.

Apple cider vinegar/Lab Interactions:
  • Potassium levelsPotassium levels: Based on potential pH altering effects of apple cider vinegar, long-term use or high doses of apple cider vinegar may reduce serum potassium levels and increase urine potassium levels (2).
  • Urinary anion gapUrinary anion gap: In one case report, long-term use of 250mL apple cider vinegar per day was associated with a high positive urinary anion gap (2).

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.