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Nickel (Ni)



Depletions

Nickel/Nutrient Depletion:
  • CalciumCalcium: According to review data, nickel may interfere with the metabolism of calcium (11; 199).
  • CholesterolCholesterol: According to review data, nickel sulfate may decrease cholesterol levels in rats (48).
  • Disulfiram (Antabuse®)Disulfiram (Antabuse®): Disulfiram chelates nickel, preventing its absorption.
  • IronIron: According to review data, nickel may interfere with the metabolism of iron and influence iron absorption from foods (11).
  • MagnesiumMagnesium: According to review data, nickel may interfere with the metabolism of magnesium (11; 374).
  • ManganeseManganese: According to review data, nickel may interfere with the metabolism of manganese (11).
  • Vitamin CVitamin C: According to review data, nickel sulfate may decrease vitamin C levels in rats (48). According to secondary sources, vitamin C reduces intestinal nickel absorption.
  • ZincZinc: According to review data, nickel may interfere with the metabolism of zinc (11; 15).

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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