Table of Contents > Interactions & Depletions > Arnica (Arnica chamissonis, Arnica cordifolia, Arnica fulgens, Arnica latifolia, Arnica montana, Arnica sororia) Print

Arnica (Arnica chamissonis, Arnica cordifolia, Arnica fulgens, Arnica latifolia, Arnica montana, Arnica sororia)



Interactions

Arnica/Drug Interactions:
  • AbortifacientsAbortifacients: Internal use of arnica is contraindicated in pregnancy due to potential for uterine stimulation (from animal and in vitro data) and toxicity (8).
  • AnalgesicsAnalgesics: Based on a randomized clinical trial, homeopathic arnica 30C may reduce subjective pain scores in tonsillectomy patients (23).
  • AnestheticsAnesthetics: According to one survey of 601 children presenting for day surgery, the use of herbal products may have serious interactions with anesthetic drugs. Arnica was one of the most common herbals used by children, and this may have implications for the perioperative management of children presenting for surgery (50).
  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: Arnica montana has been shown to increase bleeding time by inhibition of platelet aggregation in vitro (5), although no change in bleeding time was observed in a clinical trial using a homeopathic dose of arnica (49).
  • AntihypertensivesAntihypertensives: Based on anecdote, arnica may reduce the effectiveness of antihypertensives.
  • Anti inflammatory agentsAnti inflammatory agents: Based on a randomized controlled trial, arnica may reduce edema during the early postoperative period (20).
  • AntilipemicsAntilipemics: Based on animal evidence, sesquiterpene lactones may block lipogenesis, resulting in lowering of serum lipids (6).
  • CorticosteroidsCorticosteroids: Based on a randomized controlled trial, arnica may reduce edema during the early postoperative period (20).
  • Hydroxyethyl salicylateHydroxyethyl salicylate: Based on a study of healthy humans, topical arnica may increase hydroxyethyl salicylate's analgesic effect (51).

Arnica/Herb/Supplement Interactions:
  • AbortifacientsAbortifacients: Internal use of arnica is contraindicated in pregnancy due to potential for uterine stimulation (from animal and in vitro data) and toxicity (8).
  • AnalgesicsAnalgesics: Based on a randomized clinical trial, homeopathic arnica 30C may reduce subjective pain scores in tonsillectomy patients (23).
  • AnestheticsAnesthetics: According to one survey of 601 children presenting for day surgery, the use of herbal products may have serious interactions with anesthetic drugs. Arnica was one of the most common herbals used by children, and this may have implications for the perioperative management of children presenting for surgery (50).
  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: Arnica may enhance bleeding if taken with other anticoagulants, due to arnica's theoretical inhibition of platelet activation. Arnica montana has been shown to increase bleeding time by inhibition of platelet aggregation in vitro (5), although no change in bleeding time was observed in a clinical trial using a homeopathic dose of arnica (49).
  • Anti inflammatory herbsAnti inflammatory herbs: Based on a randomized controlled trial, arnica may reduce edema during the early postoperative period (20).
  • AntilipemicsAntilipemics: Sesquiterpene lactones block lipogenesis, resulting in lowering of serum lipids in mice (6).
  • Bellis perennisBellis perennis: Arnica used in conjunction with B. perennis may reduce postpartum blood loss (52).
  • HypotensivesHypotensives: Based on anecdote, arnica may reduce the effectiveness of antihypertensives.

Arnica/Food Interactions:
  • Insufficient available evidence.

Arnica/Lab Interactions:
  • Blood pressureBlood pressure: Based on anecdote, arnica may reduce the effectiveness of antihypertensives and alter blood pressure control.
  • Coagulation panelCoagulation panel: Arnica may increase coagulation time (5).
  • Lipid panelLipid panel: Theoretically, the sesquiterpene lactones in arnica may block lipogenesis, resulting in lowering of serum lipids (6).
  • Protein bindingProtein binding: Arnica may affect protein binding and therefore may alter the interpretation of in vitro and ex vivo assays (7).

Copyright © 2011 Natural Standard (www.naturalstandard.com)


The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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