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Bear's garlic (Allium ursinum)



Interactions

Bear's garlic/Drug Interactions:
  • Anti inflammatory agentsAnti inflammatory agents: Bear's garlic has demonstrated inhibitory activity on 5-lipoxygenase, cyclooxygenase, thrombocyte aggregation, and angiotensin I-converting enzyme (8). These findings suggest that bear's garlic has the potential to potentiate the activity of non-steroidal anti-inflammatory drugs.
  • Antiplatelet agentsAntiplatelet agents: Isolated compounds in bear's garlic have demonstrated inhibition of human platelet aggregation (1). Moreover, Bear's garlic demonstrated inhibitory activity on 5-lipoxygenase (LO), cyclooxygenase (CO), thrombocyte aggregation (TA), and angiotensin I-converting enzyme (ACE) (8). These findings suggest that bear's garlic has the potential to potentiate the activity of antiplatelet agents.

Bear's garlic/Herb/Supplement Interactions:
  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: Isolated compounds in bear's garlic have demonstrated inhibition of human platelet aggregation (1). Moreover, bear's garlic has shown inhibitory activity on 5-lipoxygenase, cyclooxygenase, thrombocyte aggregation, and angiotensin I-converting enzyme (8). These findings suggest that bear's garlic has the potential to potentiate the activity of herbs with antiplatelet activity.
  • Anti inflammatory herbsAnti inflammatory herbs: Bear's garlic has demonstrated inhibitory activity on 5-lipoxygenase, cyclooxygenase, thrombocyte aggregation, and angiotensin I-converting enzyme (8). These findings suggest that bear's garlic has the potential to potentiate the activity of herbs with anti-inflammatory activity.

Bear's garlic/Food Interactions:
  • Insufficient available evidence.

Bear's garlic/Lab Interactions:
  • Coagulation panelCoagulation panel: Isolated compounds in bear's garlic have demonstrated inhibition of human platelet aggregation (1; 8). Moreover, similar concentrations of S-containing compounds (thiosulfinates and ajoenes) and similar inhibitory activity on 5-lipoxygenase, cyclooxygenase, thrombocyte aggregation, and angiotensin I-converting enzyme were observed (8). These findings suggest that bear's garlic has the potential to impact coagulation panel results.

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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