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Lidocaine and Prilocaine


Related terms
Author information


    Related terms
    • U.S. Brand Names: EMLA®;Oraqix®
    • Canadian Brand Names: EMLA®
    • Mexican Brand Names: Emla
    • Pharmacologic Category: Local Anesthetic

    • This medicine is used to prevent pain from shots.
    • This medicine is used before dental procedures to numb the area.
    • Lidocaine and prilocaine numbs the area.


    How to take

    • Cream:
    • Apply 1 hour before shot.
    • Do not take this medicine by mouth. For skin only. Keep out of mouth, nose, and eyes (may burn).
    • Clean affected area before use. Make sure to dry well.
    • Use a rubber glove to apply.
    • Apply a thick layer to the area where the shot is to be given. Do not rub in.
    • Cover the area with a bandage or dressing.
    • Gel:
    • Will be applied by healthcare provider.


    • Store at room temperature.



    • If you have an allergy to lidocaine, prilocaine, or any other part of this medicine.
    • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.


    • If you have liver disease, talk with healthcare provider.
    • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
    • Use caution on skin where a large area is involved or where there are open wounds.
    • Tell healthcare provider if you are pregnant or plan on getting pregnant.
    • Tell healthcare provider if you are breast-feeding.

    Side Effects

    • Cream:
    • Skin irritation.
    • Gel:
    • Abnormal taste.
    • Nausea.
    • Mouth irritation.


    • Change in condition being treated. Is it better, worse, or about the same?

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or emergency department immediately.
    • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
    • Fast heartbeat.
    • Difficulty breathing.
    • Severe dizziness or passing out.
    • Severe skin irritation.
    • Any rash.
    • No improvement in condition or feeling worse.

    General Statements

    • If you have a life-threatening allergy, wear allergy identification at all times.
    • Do not share your medicine with others and do not take anyone else's medicine.
    • Keep all medicine out of the reach of children and pets.
    • Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
    • Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
    • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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