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WM-2000™

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Related terms
Background
Theory/evidence
Safety
Author information
Bibliography

Related Terms
  • Bladderwrack, brindall berry, CLA, Eleutherococcus senticosus, Flavo-Magic®, Formula S/B®, Formula S/E®, Forte®, garcinia, Garcinia cambogia, ginger, Gluco-Shield®, gymnema, Gymnema sylvestre, H&Ms Chocoberry Chews®, Herbal Magic®, kelp, L-Glutabolic®, Lean Extreme®, Lessonia nigrescens, Maintenance-Optimizer®, PB-5®, Platinum 2000®, Relaxatrim®, Siberian ginseng, VHP®, WM-4000 Ultra®, Zingiber officinale.

Background
  • WM-2000T, manufactured by Herbal Magic®, is an herbal dietary supplement that consists of Siberian ginseng (Eleutherococcus senticosus), brindall berry (Garcinia cambogia), ginger root (Zingiber officinale), gymnema (Gymnema sylvestre), and kelp (Lessonia nigrescens).
  • According to manufacturer data, the herbs in WM-2000T are combined to aid in weight loss and are intended to be used as a part of a complete weight-loss program. However, there is currently a lack of scientific data on the safety and effectiveness of WM-2000T.
  • Some research is available on the individual ingredients in WM-2000T.

Theory / Evidence
  • General: According to manufacturer data, the herbs in WM-2000T are combined to aid in weight loss. Although there is currently a lack of scientific data on the safety and effectiveness of WM-2000T, some research is available on the individual ingredients.
  • Siberian ginseng: Siberian ginseng (Eleutherococcus senticosus) is a small, woody shrub in the Araliaceae family that is native to northeastern Asia. It is unrelated to true ginseng (Panax ginseng); however, the name "Siberian ginseng" became popular based on potential properties that are similar to Panax ginseng.
  • Siberian ginseng has been traditionally used in Asia for a wide variety of conditions. It has been suggested as a potential adaptogen and exercise performance enhancer, but evidence of effectiveness is insufficient. Additional research is also needed to determine whether it is beneficial for cancer, chronic fatigue syndrome, familial Mediterranean fever, genital herpes hypotension (neurocirculatory), immune disorders, menopause, pneumonia, quality of life, and respiratory tract infections.
  • Brindall berry: Brindall berry, also called garcinia, is a purple fruit that is native to India and Southeast Asia. It contains high levels of hydroxycitric acid (HCA), which is used as a weight-loss aid. An extract of (-)-hydroxycitric acid (HCA-SX) in combination with niacin-bound chromium and Gymnema sylvestre extract has been reported to reduce appetite, inhibit fat synthesis, and decrease body weight without stimulating the central nervous system. However, overall, the available evidence is inconclusive.
  • Ginger: Ginger (Zingiber officinale) has been used extensively in Chinese, Japanese, and Indian medicine since the 1500s. The oleoresin of ginger is often contained in digestive, antitussive, antiflatulent, laxative, and antacid formulations.
  • Ginger has been shown to reduce the severity and duration of nausea/emesis during pregnancy and may have beneficial effects on other types of nausea, such as chemotherapy-induced nausea, postoperative nausea, or motion sickness.
  • Ginger has also been suggested as a possible weight loss aid; however, definitive supportive evidence for this use is currently lacking. Based on early study, spiced foods or herbal drinks, such as those that contain ginger, may have the potential to produce significant neurologic and metabolic effects, such as an increase in satiety and breakdown of fats. In one clinical trial, an herbal combination product containing ginger was found to be ineffective for weight loss in healthy adults. However, because ginger was combined with other herbs, the effects cannot be attributed to ginger alone. Additional studies are needed.
  • There is also unclear or conflicting scientific evidence on its effectiveness for bleeding disorders, migraine, arthritis, labor and urinary disorders after a stroke.
  • Gymnema: Gymnema (Gymnema sylvestre) has been used for more than 2,000 years in India. It has been shown to lower serum glucose levels following chronic use but may not have significant acute effects. Preliminary human research reports that gymnema may be beneficial in patients with type 1 or type 2 diabetes when taken with oral diabetes medications or insulin. It may also help lower cholesterol and triglyceride levels in patients with type 2 diabetes.
  • Limited research suggests that Gymnema sylvestre extract (GSE) may be effective for weight loss when used in combination with other products such as (-)-hydroxycitric acid (HCA-SX). However, additional high-quality trials using gymnema alone are needed to confirm early study results.
  • Kelp: Kelp are various types of seaweed that are consumed as food in different forms. As an herbal medicine, kelp has been used for cough, asthma, hemorrhoid, boils, goiters, stomach ailments, and urinary diseases, as well as for reducing the incidence of tumors, ulcers, and headaches.
  • Kelp has traditionally been used to treat disorders of the thyroid gland and is included as a component of various weight-loss formulas. Theoretically, the thyroid-stimulatory properties of kelp may cause weight loss. However, its effectiveness and safety for this use have not been adequately studied in humans. There is currently a lack of available high-quality trials of kelp for any indication.
  • Kelp has also been shown to possess blood sugar-lowering and blood-thinning properties.

Safety




Author information
  • This information has been edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).

Bibliography
  1. Burman KD, Wartofsky L. Iodine effects on the thyroid gland: biochemical and clinical aspects. Rev Endocr Metab Disord. 2000 Jan;1(1-2):19-25.
  2. Downs BW, Bagchi M, Subbaraju GV, Shara MA, Preuss HG, Bagchi D. Bioefficacy of a novel calcium-potassium salt of (-)-hydroxycitric acid. Mutat Res. 2005 Nov 11;579(1-2):149-62. Epub 2005 Aug 1.
  3. Goyal RK, Kadnur SV. Beneficial effects of Zingiber officinale on goldthioglucose induced obesity. Fitoterapia. 2006 Apr;77(3):160-3. Epub 2006 Feb 28.
  4. Hasani-Ranjbar S, Nayebi N, Larijani B, Abdollahi M. A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity. World J Gastroenterol. 2009 Jul 7;15(25):3073-85.
  5. Hayamizu K, Tomi H, Kaneko I, Shen M, Soni MG, Yoshino G. Effects of Garcinia cambogia extract on serum sex hormones in overweight subjects. Fitoterapia. 2008 Jun;79(4):255-61. Epub 2008 Feb 9.
  6. Knudsen N, Laurberg P, Rasmussen LB, Bülow I, Perrild H, Ovesen L, Jřrgensen T. Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population. J Clin Endocrinol Metab. 2005 Jul;90(7):4019-24. Epub 2005 May 3.
  7. Mattes RD, Bormann L. Effects of (-)-hydroxycitric acid on appetitive variables. Physiol Behav. 2000 Oct 1-15;71(1-2):87-94.
  8. Natural Standard: The Authority on Integrative Medicine.
  9. Ohia SE, Opere CA, LeDay AM, Bagchi M, Bagchi D, Stohs SJ. Safety and mechanism of appetite suppression by a novel hydroxycitric acid extract (HCA-SX). Mol Cell Biochem. 2002 Sep;238(1-2):89-103.
  10. Preuss HG, Bagchi D, Bagchi M, Rao CV, Dey DK, Satyanarayana S. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab. 2004 May;6(3):171-80.
  11. Roy S, Shah H, Rink C, Khanna S, Bagchi D, Bagchi M, Sen CK. Transcriptome of primary adipocytes from obese women in response to a novel hydroxycitric acid-based dietary supplement. DNA Cell Biol. 2007 Sep;26(9):627-39.
  12. Szolomicki J, Samochowiec L, Wójcicki J, Drozdzik M. The influence of active components of Eleutherococcus senticosus on cellular defence and physical fitness in man. Phytother Res. 2000 Feb;14(1):30-5. Erratum in: Phytother Res 2000 May;14(3):225.
  13. Westerterp-Plantenga M, Diepvens, K, Joosen, AM, et al. Metabolic effects of spices, teas, and caffeine. Physiol Behav 8-30-2006;89(1):85-91.
  14. WM-2000T product monograph. Herbal Magic® Weight Loss and Nutrition Centers, 2009.
  15. Woodgate DE, Conquer JA. Effects of a stimulant-free dietary supplement on body weight and fat lass in obese adults: a six-week exploratory study. Current Therapeutic Research. 2003;64(4).

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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