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Hyacinth bean (Lablab spp.)

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Also listed as: Lablab spp.
Related terms
Background
Evidencetable
Tradition
Dosing
Safety
Interactions
Attribution
Bibliography

Related Terms
  • Arabinose, arcelin, arginase, batao, chè d?u ván (Vietnamese), chikusetsusaponin IVa, country bean, cyanogenic glucosides, d?u ván (Vietnamese), dolicholin, Dolichos lablab spp., Dolichos purpureus L., Egyptian bean, Fabaceae (family), field bean, French bean, glutamic-aspartic transaminase, Indian bean, lablab, Lablab lablab, Lablab niger Medikus, Lablab purpureus spp., lablab saponin I, Lablab vulgaris, lablabosides, oleanane-type triterpene bisdesmosides, phytoagglutinins, polyphenol oxidase, raffinose, stachyose, verbascose, Vigna artistata Piper.

Background
  • Hyacinth bean (Lablab spp.) is found in tropical areas, where it is commonly used as a food crop. Hyacinth bean has also been used as a medicine, poison, or fertilizer, and for ornamental purposes.
  • Hyacinth bean has been shown to decrease the risk of bleeding and may have contraceptive, insecticide, nutrition enhancement, antioxidant, and antiviral effects, however, there is currently a lack of human trials in these areas. Further research is necessary before conclusions may be made regarding using hyacinth bean for any condition.

Evidence Table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. GRADE *
* Key to grades

A: Strong scientific evidence for this use
B: Good scientific evidence for this use
C: Unclear scientific evidence for this use
D: Fair scientific evidence for this use (it may not work)
F: Strong scientific evidence against this use (it likley does not work)


Tradition / Theory

The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.

  • Antifungal, antioxidant, contraception, food uses, HIV, insecticide, nutritional support.

Dosing

Adults (18 years and older)

  • Insufficient available evidence.

Children (under 18 years old)

  • Insufficient available evidence.

Safety

The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.

Allergies

  • Avoid with known allergy or hypersensitivity to hyacinth bean (Lablab spp.), its constituents, or members of the Fabaceae family, such as peas and beans.

Side Effects and Warnings

  • Hyacinth bean may cause flatulence (gas).
  • Hyacinth bean may decrease the risk of bleeding. Caution is advised in patients with bleeding disorders or those taking drugs, herbs, or supplements that may increase the risk of bleeding. Dosing adjustments may be necessary.
  • Use cautiously in patients using fertility agents or in women trying to become pregnant, as hyacinth bean may have birth control effects.
  • Avoid consumption of dry seeds from the hyacinth bean plant, as they may be poisonous; seeds from the hyacinth bean plant should only be eaten after prolonged boiling.
  • Avoid in pregnant or breastfeeding women, due to a lack of available scientific evidence.
  • Avoid in individuals with known allergy or hypersensitivity to hyacinth bean (Lablab spp.), its constituents, or members of the Fabaceae family, such as peas and beans.

Pregnancy and Breastfeeding

  • Avoid in pregnant or breastfeeding women, due to a lack of safety information.
  • Information on hyacinth bean's effects on lactation is currently lacking in the National Institute of Health's Lactation and Toxicology Database (LactMed).

Interactions

Interactions with Drugs

  • Hyacinth bean may decrease the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants (blood thinners) such as warfarin (Coumadin®) or heparin, antiplatelet drugs such as clopidogrel (Plavix®), and nonsteroidal anti-inflammatory drugs such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).
  • Hyacinth bean may also interact with agents that stimulate the immune system, anticancer agents, antifungals, antiretroviral agents, fertility agents, gastrointestinal agents, and proteinase inhibitors (antiviral agents).

Interactions with Herbs and Dietary Supplements

  • Hyacinth bean may decrease the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto. Numerous other agents may theoretically increase the risk of bleeding, although this has not been proven in most cases.
  • Hyacinth bean may also interact with anticancer herbs and supplements, antifungals, antioxidants, antivirals, fertility herbs and supplements, gastrointestinal herbs and supplements, and herbs and supplements that stimulate the immune system.

Attribution
  • This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).

Bibliography
  1. Abeke FO, Ogundipe SO, Sekoni AA, et al. Growth and subsequent egg production performance of shika-brown pullets fed graded levels of cooked beans. Pak J Biol Sci 2007;10(7):1056-1061.
  2. Baligar VC, Fageria NK, Paiva AQ, et al. Light intensity effects on growth and micronutrient uptake by tropical legume cover crops. Journal of Plant Nutrition 2006;29(11):1958-1974.
  3. Gubesch M, Theler B, Dutta M, et al. Strategy for allergenicity assessment of 'natural novel foods': clinical and molecular investigation of exotic vegetables (water spinach, hyacinth bean and Ethiopian eggplant). Allergy 2007;62(11):1243-1250.
  4. Janarthanan S, Suresh P, Radke G, et al. Arcelins from an Indian wild pulse, , and insecticidal activity in storage pests. J Agric.Food Chem 2008;56(5):1676-1682.
  5. Kanade SR, Rao DH, Hegde RN, et al. The unique enzymatic function of field bean (Dolichos lablab) D-galactose specific lectin: a polyphenol oxidase. Glycoconj J 2009;26(5):535-545.
  6. Kim YH, Woloshuk CP, Cho EH, et al. Cloning and functional expression of the gene encoding an inhibitor against Aspergillus flavus alpha-amylase, a novel seed lectin from Lablab purpureus (Dolichos lablab). Plant Cell Rep 2007;26(4):395-405.
  7. Kone AW, Tondoh JE, Bernhard-Reversat F, et al. Changes in soil biological quality under legume- and maize-based farming systems in a humid savanna zone of Côte d'Ivoire. Biotechnol Agron Soc 2008;12(2):147-155.
  8. Latha VL, Rao RN, Nadimpalli SK. Affinity purification, physicochemical and immunological characterization of a galactose-specific lectin from the seeds of (Indian lablab beans). Protein Expr Purif 2006;45(2):296-306.
  9. Qureshi SA, Midmore DJ, Syeda SS, et al. A comparison of alternative plant mixes for conservation bio-control by native beneficial arthropods in vegetable cropping systems in Queensland Australia. Bull Entomol Res 2010;100(1):67-73.
  10. Rameshwaram NR, Karanam NK, Scharf C, et al. Complete primary structure of a newly characterized galactose-specific lectin from the seeds of . Glycoconj J 2009;26(2):161-172.
  11. Schellenberger DL, Morse RD, Welbaum GE. Organic broccoli production on transition soils: Comparing cover crops, tillage and sidedress N. Renewable Agriculture & Food Systems 2009;24(2):85-91.
  12. Sufian MK, Hira T, Asano K, et al. Peptides derived from dolicholin, a phaseolin-like protein in country beans (), potently stimulate cholecystokinin secretion from enteroendocrine STC-1 cells. J Agric Food Chem 2007;55(22):8980-8986.
  13. Vanlauwe B, Idrissa A, Diels J, et al. Plant age and rock phosphate effects on the organic resource quality of herbaceous legume residues and their N and P release dynamics. Agron Sustain Dev 2008;28(3):429-437.
  14. Vera-Nunez JA, Infante-Santiago JP, Velasco V, et al. Influence of P Fertilization on Biological Nitrogen Fixation in Herbaceous Legumes Grown in Acid Savannah Soils from the Tabasco State, Mexico. Journal of Sustainable Agriculture 2008;31(3):25-42.
  15. Yao H, Xie X, Li Y, et al. Legume lectin FRIL preserves neural progenitor cells in suspension culture in vitro. Clin Dev Immunol 2008;2008:531317.

Copyright © 2011 Natural Standard (www.naturalstandard.com)


The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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