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Goat's rue (Galega officinalis)



Interactions

Galega officinalis/Drug Interactions:
  • AntibioticsAntibiotics: In vitro, alcoholic extracts of Galega officinalis have exhibited significant inhibition on the growth of various types of Gram-positive and Gram-negative bacteria (10).
  • AntidiabeticsAntidiabetics: In animal research, an intragastric infusion of dry extract or galegine sulfate, a constituent of Galega, resulted in a 32% reduction in blood glucose (1). Based on this study, a potential interaction may exist with other hypoglycemic medications.
  • Antiobesity agentsAntiobesity agents: In animal research, galegine and Galega herb (10% w/w in the diet) have shown a weight-reducing effect (21; 3; 4; 5; 6).
  • AntiplateletsAntiplatelets: In animal and in vitro research, an extract of Galega officinalis inhibited platelet aggregation (2; 3; 4; 5; 6).
  • Iron saltsIron salts: Galega officinalis may interfere with the absorption of iron and other minerals, according to secondary sources.

Galega officinalis/Herb/Supplement Interactions:
  • AntibacterialsAntibacterials: In vitro, alcoholic extracts of Galega officinalis have exhibited significant inhibition on the growth of various types of Gram-positive and Gram-negative bacteria (10).
  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: In animal and in vitro research, an extract of Galega officinalis inhibited platelet aggregation (2; 3; 4; 5; 6).
  • Antiobesity agentsAntiobesity agents: In animal research, galegine and Galega herb (10% w/w in the diet) have shown a weight-reducing effect (21; 3; 4; 5; 6).
  • HypoglycemicsHypoglycemics: In animal research, an intragastric infusion of dry extract or galegine sulfate, a constituent of Galega, resulted in a 32% reduction in blood glucose (1). Based on this study, a potential interaction may exist with other hypoglycemic medications.
  • IronIron: Galega officinalis may interfere with the absorption of iron and other minerals, according to secondary sources.

Galega officinalis/Food Interactions:
  • Iron-containing foodsIron-containing foods: Galega officinalis may interfere with the absorption of iron and other minerals, according to secondary sources.

Galega officinalis/Lab Interactions:
  • Blood glucoseBlood glucose: In animal research, an intragastric infusion of dry extract or galegine sulfate, a constituent of Galega, resulted in a 32% reduction in blood glucose (1).
  • Coagulation panelCoagulation panel: In animal and in vitro research, an extract of Galega officinalis inhibited platelet aggregation (2; 3; 4; 5; 6).
  • WeightWeight: In animal research, galegine and Galega herb (10% w/w in the diet) have shown a weight-reducing effect (21; 3; 4; 5; 6).

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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